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Giuseppe Garcea, Ashley Dennison


Background: Chronic diseases are the leading cause of mortality and morbidity in Europe and research suggests that complex conditions such as diabetes, obesity and depression will impose an even larger burden on health services in the future. The accurate profiling of immediate costs of these conditions is essential in planning healthcare.

Methods: A literature search incorporating peer-reviewed papers, electronic resources and consensus documents was undertaken.

Results: Modelling the costs of chronic disease is a complex process. Various mathematical formulae and software exists to make this as accurate as possible.

Conclusion:Assessing the burden of disease, its direct costs and also the indirect impact which chronic disease has on subsequent GDP, is a difficult task. However, such benchmarking is essential to formulate effective future health strategies, including ones advocating more person-centered approaches in clinical practice.


Chronic disease, chronic long term illness, efficiency in healthcare, health economics, mathematical modelling, morbidity, mortality, person-centered care, treatment expenditure

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